Some of these questions have been taken from
other Animal Physiology pages. All questions require answers that fully explain
the conditions, causes, and results.
Some of these questions
have been taken other Animal Physiology pages. All questions require answers
that fully explain the conditions, causes, and results.
Chapter 23 GAS TRANSPORT
REVIEW QUESTIONS
- One could say that a respiratory pigment with relatively low O2 affinity
is potentially disadvantageous for loading, but advantageous for unloading.
Explain both parts of this statement.
- Outline the ways in which mammalian hemoglobin simultaneously plays
important roles in O2 transport, CO2 transport, and control of blood pH..
- The hemoglobin in mammalian blood is usually thought of simply increasing
the amount of oxygen that can be carried by each liter of blood. In a lecture
on hemoglobin, a respiratory physiologist made the following statement: "The
presence of hemoglobin in the blood also makes possible the rapid uptake of
oxygen by the blood as it flows through the lungs." Explain the lecturer’s
point.
- What are the two principal reasons for enclosing oxygen carrying proteins
in blood cells?
- What is the functional significance of the typical sigmoid shape (Fig.
23.4) of the hemoglobin-oxygen dissociation curve? What is the advantage of
the shape of the curve at oxygen partial pressures > 80 mm Hg; < 40 mm Hg.
- Using Fig 23.5, show how much more oxygen is released to tissues doing
exercise versus tissues at rest.
- For Fig. 23.6, how much of a drop in O2 partial pressure is required to
cause unloading of 5 vol % O2 if the initial concentration is 20 ml O2/100 ml?
10 ml O2/100 ml? Show how you calculated this.
- What is the significance of Figure 23.7? Why does the curve for myoglobin
have a hyperbolic shape and the curve for hemoglobin a sigmoid shape? Why is
the curve for myoglobin to the left of the curve for hemoglobin? What is the
physiological significance of this for oxygen transport?
- Discuss the interaction between hemoglobin and myoglobin. Illustrate your
answer with a graph (e.g., Fig 23.7) showing oxygen dissociation. Use actual
numbers from the graph to show how it works.
- What is P50, and how is it related to the oxygen affinity of a respiratory
pigment?
- Draw a hemoglobin-oxygen dissociation curve. What label should be given
along the X-axis; the Y-axis? Circle the region of the graph that would be
representative of the conditions in a mammalian alveolus of a lung; in a
tissue capillary bed. What is the P50 for your graph?
- From a single oxygen-hemoglobin (i.e., no Bohr effect) dissociation curve,
be able to determine and/or explain what the saturation will be for a given
oxygen pressure; the oxygen pressure for a given saturation; the P50; the
oxygen pressure and saturation in the respiratory organs; the oxygen pressure
and saturation in the deep tissues; the change in oxygen pressure and
saturation going from the respiratory organs to the deep tissues; and the
change in oxygen pressure and saturation going from deep tissues to the
respiratory organs.
- What is the Bohr Effect?
- Explain why higher temperatures tend to shift the Hb-O2 dissociation curve
to the right.
- How does blood pH influence the Hb-O2 dissociation curve?
- Draw a single oxygen-hemoglobin (i.e., no Bohr effect) dissociation curve
for a mammal with correctly labeled X and Y axes (e.g., a figure similar to
Fig. 23.5). Blood leaving the lungs carries 20 ml O2 / 100 ml. From this
curve, calculate the amount of oxygen that 100 ml of blood will unload to the
respiring tissue. Show your work or no credit. Now do same for a graph showing
the Bohr Effect (i.e., with two oxygen dissociation curves, (Fig. 23.11).
- Fully explain a figure showing the Bohr Effect (e.g., Fig. 23.11). Include
information about what each of the two curves represent, what causes them to
differ from each other, what is the advantage of each, and give an example of
where each of the two is operating. Discuss an actual example with approximate
real values of saturation %'s and oxygen pressures to demonstrate the adaptive
advantage of this system.
- Examine and be sure you understand the graph Figure 23.11. Explain in
words what is shown on the y-axis. What is shown on the x-axis? Discuss what
each of the two curves represent, what causes them to differ from each other,
what is the advantage of each, and give an example of where each of the two is
operating. Discuss an actual example with approximate real values of
saturation %'s and oxygen pressures to demonstrate the adaptive advantage of
this system.
- How does DPG affect the P50 of the blood (e.g. Fig.23.14 and 23.15)? What
is the biochemical mechanism?
- How and why do humans at high elevations change their DPG levels?
- How and why do humans with anemia change their DPG levels?
- Discuss how and where carbon dioxide is transported in the blood.
- What are the chemical reactions that allow increased ability of the blood
to transport higher amounts of carbon dioxide at higher partial pressures (Fig
23.20a)?
- Explain what is being shown in Figure 23.21a, i.e. the Haldane Effect.
- Explain Fig. 23.21b. What is the physiological significance of the Haldane
Effect for humans who are exercising?
- What is the role of carbonic anhydrase in the deep tissues? In the lungs?
- Why is the enzyme carbonic anhydrase so critical for respiratory exchange
in the circulatory system?
- Define, explain the importance to respiratory physiology, and give an
example of the following
- Respiratory pigment
- Hemocyanin
- Hemoglobin
- Erythrocyte
- Cooperativity
- P50
- Bohr Effect
- DPG (bisphosphoglycerate)
- erythropoietin
- Haldane effect
- Carbonic anhydrase
CHAPTER 24 Circulation
REVIEW QUESTIONS
- What functions does the
circulatory system perform?
- Know the path of
circulation from the veins through the heart to the arteries. Be able to
label all the features shown in Fig. 24.1.
- What is occurring during
systole? During diastole?
- How and why does
ventricular pressure differ on the left and right sides of the heart?
- Explain what is occurring
during the five phases of the heart cycle shown in Figure 24.2.
- Atriole systole
- Isovolumetric
contraction
- Ventricular ejection
- Isovolumetric
relaxation
- Ventricular filling
- How do atriole systole
and ventricular relaxation add to the end diastolic volume? Which is more
important?
- At what stage do the
atrio-ventricular valves close? What causes this?
- At what stage do the
atrio-ventricular valves open? What causes this?
- At what stage do the
pulmonary and aortic valves close? What causes this?
- At what stage do the
pulmonary and aortic valves open? What causes this?
- Why isn’t blood ejected
during isovolumetric contraction?
- You should know that
Cardiac output = (Heart Rate)*(Stroke Volume)
- If a normal cardiac
output is 6 liters/minute (when the person is at rest), use your resting
heart rate to find out the stroke volume.
- From the blood capacity,
beat volume, and pulse rate, be able to determine the amount of oxygen being
transported by the circulatory system. For example, use the capacity = 20 ml
O2 / 100 ml blood, pulse rate = 60 beats per minute, and the stroke
volume = 70 ml
- What causes the heart
sounds heard with a stethoscope?
- What happens when heart
muscles depolarize? Repolarize?
- How is heartbeat
regulated in mammals?
- What is the pacemaker?
How does it control heart rate?
- Why to the ventricles
contract after the atria?
- Briefly discuss the
processes occurring during the wave of depolarization of the contraction cycle
of the heart (Fig. 24.4b).
- Explain what is shown in
the electrocardiogram of a normal human heart (Fig. 24.6).
- What does the P wave
signify? The QRS complex? The T wave?
- What is the
Frank-Starling Law of the heart? What is its significance?
- How do positional effects
affect blood pressure (Figure 24.7)?
- Discuss and explain blood
pressure at your feet, heart, and head when you are standing up and when you
are lying down.
- Compare and contrast
blood pressure in a human and a giraffe.
- What animal phyla lack
circulatory systems? How do they respire?
- Compare and contrast an
open and closed circulatory system.
- Compare and contrast
arteries, veins, and capillaries. ?
- Illustrate and describe
the circulatory system of a typical bird or mammal (Fig. 24.10).
- Illustrate and describe
the general path of flow of blood through the circulatory system of a mammal.
- How does the heart of a
bird or a mammal differ from that of a typical reptile? What are the
advantages of this arrangement?
- How does cross sectional
area affect flow rate?
- Discuss and explain the
changes in cross-sectional area from the arteries to the capillaries to the
veins (Figure 24.12a).
- Why does blood pressure
decrease from the arteries to the capillaries? Explain Figure 24.12b.
- Discuss and illustrate
what happens as blood flows through capillaries (Fig. 24.13).
- What happens to excess
fluid that leaves the capillaries and remains in the interstitial fluids?
- What is the blood
pressure in the venous system? What two mechanisms move blood pressure back
to the heart?
- How does the circulatory
system of cephalopods differ from that of other mollusks? Why?
- Illustrate and describe
the anatomical arrangement of the heart of a teleost fish or shark (e.g., Fig.
24.14).
- Illustrate and describe
the circulatory system of a teleost fish (e.g., Fig. 24.14). Discuss the
oxygen and blood pressure changes that occur in the circuit. How is blood
pumped to complete the circuit?
- Describe the basic
anatomy and pattern of blood flow of the amphibian heart. How does it differ
from the fish heart?
- Does deoxygenated and
oxygenated blood mix together in the undivided ventricle of amphibians? Why?
- Compare and contrast a
typical reptilian heart and the heart of a mammal (or bird). Explain the
significance of the differences.
Define, explain the importance to the physiology of circulation, and give an
example of the following
- Diffusion
- Systole
- Diastole
- Cardiac cycle
- Isovolumetric contraction
- Ventricular ejection
- Cardiac output
- Stroke volume
- Heart murmur
- Myogenic
- Sinoatrial node
- Pacemaker
- Atrioventricular node
- Electrocardiogram
- Starling's Law of the
Heart
- Interstitial fluid
- Blood
- Lymph
- Closed circulatory
system.
- Open circulatory system.
- Artery
- Vein
- Capillary
- Pulmonary circulation
- Systemic circulation
- Colloidal osmotic
pressure of the capillaries
- Hydrostatic pressure of
the capillaries
- Lymphatic system
- Erythrocyte
CHAPTER 25 Diving
Mammals
REVIEW QUESTIONS
1.
Which tissues need the most energy during diving?
2.
Which tissues need the most O2?
3.
Compare the blood oxygen stores of terrestrial and marine mammals. How
do they differ in carrying capacity? Blood volume?
4.
Compare and discuss the reasons for the different total as well as the
individual lung, blood, and myoglobin oxygen stores of humans, shallow diving
mammals, and deep diving mammals. (see Figure 25.6)
5.
How is oxygen supply maximized in diving mammals? Where is it stored?
6.
Compare oxygen storage in a marine mammal and a human.
7.
Outline the pros and cons of carrying lots of air during a dive.
8.
How does the circulatory system respond to extended dives by whales and
seals?
9.
How does the pattern of circulation pattern in a marine mammal during a
deep dive? Why?
10.
How can the muscles of marine mammals function if there is no oxygen
available for them to contract?
11.
Why is it important to reduce the heart rate during a dive?
12.
What is produced by anaerobic metabolism in animals? What potential
problems does this cause? How is this minimized?
13.
Discuss oxygen levels in the blood and muscles during the course of a
deep dive (Fig. 25.10a)
14.
Discuss lactic acid levels in the blood and muscles during the course of
a deep dive (Fig. 25.10b)
15.
Discuss what is happening to lactic acid levels in the blood following a
deep dive (Fig. 25.11
16.
Based on the study of O2 needs and stores, the aerobic dive
limit of young Weddell seals weighing 140 kg is calculated to be 10 minutes,
whereas that for a fully grown 400-kg Weddell seal is calculated to be about 20
minutes. Why might small individuals in general be expected to have shorter
aerobic dive limits than large individuals?
17.
What is decompression sickness (the "bends)?"
18.
Why is only nitrogen and not carbon dioxide or oxygen that divers have to
worry about when breathing compressed air?
19.
Why do humans get the bends and how does the Weddell Seal avoid the
problem?
20.
Why aren’t deep diving marine mammals affected by nitrogen narcosis?
Define, explain the
importance to the physiology of diving mammals, and give an example of the
following
21.
Hypoxia
22.
Carrying capacity
23.
Total blood stores of oxygen
24.
myoglobin
25.
Diving response
26.
Bradycardia
27.
Peripheral vasoconstriction
28.
Oxygen debt
29.
Aerobic dive limit
30.
Decompression sickness or the “bends”
31.
Nitrogen narcosis
32.
Oxygen toxicity
CHAPTER
26: OSMOREGULATION and
EXCRETION
REVIEW QUESTIONS
- What is the difference
between interstitial and intracellular fluid? Why are they usually
different?
- How are ionoregulation
and osmoregulation similar?
- What is the difference
between ionoregulation and osmoregulation?
- What are the benefits of
ionoregulation and osmoregulation?
- What are the costs of
ionoregulation and osmoregulation?
- Discuss what is being
shown in Figs 26.3a and 26.3b in regard to osmoregulation and osmoconformity.
- In figure 26.3c, how are
the green crab, mussel, and shrimp responding to changes in salinity.
- Why are there no
freshwater osmoconformers?
- Compare and contrast the
advantages and disadvantages of being an osmoconformer versus an osmoregulator.
- What are the three
sources of water for animals?
- What is the disadvantage
of drinking salty water?
- How do kangaroo rats
survive without having to drink water?
Define, explain the importance to animal physiology, and give an example of the
following
- Osmoregulation
- Ionoregulation
- Excretion
- Isosmotic animal
- Hyperosmotic animal
- Hyposmotic
- Drinking water
- Dietary water
- Metabolic water
Chapter
27 Water and Salt Physiology
REVIEW QUESTIONS
- Fig 27.1 shows water–salt
relations in a freshwater animal. Be able to label and discuss the major
sources of movement of salts and water in and out of the organism and the
mechanisms (diffusion, etc.) responsible.
- Fig 27.7a shows
water–salt relations in a freshwater bony fish. Be able to label and discuss
the major sources of movement of salts and water in and out of the organism
and the mechanisms (diffusion, etc.) responsible.
- Fig 27.7b shows
water–salt relations in a marine bony fish. Be able to label and discuss the
major sources of movement of salts and water in and out of the organism and
the mechanisms (diffusion, etc.) responsible. .
- Fig 27.9 shows water–salt
relations in a marine shark. Be able to label and discuss the major sources
of movement of salts and water in and out of the organism and the mechanisms
(diffusion, etc.) responsible.
- What are the main osmotic
and ionic challenges of freshwater teleosts (advanced bony fish) and how are
these challenges met?
- What is the role of the
integument in osmoregulation?
- What osmoregulatory
problems do most marine vertebrates face?
- What are the main osmotic
and ionic challenges of marine teleosts and how are these challenges met?
- How do hagfish
osmoregulate?
- Discuss osmoregulation in
the life cycle of sea lampreys.
- How do sharks (elasmobranchs)
avoid water loss in salt water?
- How do marine sharks (elasmobranchs)
regulate water and salt?
- Explain how Latimeria
(the coelacanth) and marine elasmobranchs solve the osmotic problem of a
vertebrate in sea water and why their bodies are slightly hyperosmotic
- Describe osmoregulation
in marine elasmobranchs. How are urea and TMAO important to this process?
- Review the strategies for
salt and water balance in aquatic animals that live in-between fresh water and
the marine environment. What is a hyper-isosmotic regulator; a hyper-hyposmotic
regulator?
- Why is a teleost fish in
the ocean like a desert animal?
- Explain osmotic and ion
(salt) regulation in marine and fresh water teleosts.
- Explain how the salmon is
able to osmotically move between fresh water and sea water.
- Explain osmotic and ion
(salt) regulation in fresh-water amphibians.
- Compare and contrast the
osmoregulatory strategies used by, marine invertebrates, marine teleosts and
freshwater teleosts. For each you must mention the relative osmolarity of
their body fluids to that of the environment in which they live.
- Cite the greatest
advantage and disadvantage of terrestrial life.
- Why do amphibians face
greater osmotic regulation problems than other terrestrial vertebrates? How
do some frogs and toads minimize this problem?
- List the various ways by
which water is gained or lost in terrestrial animals.
- How do kangaroo rats
maintain water balance? How are they able to survive in hot dry deserts?
- Identify how marine
reptiles and birds regulate their salt balance.
Define, explain the importance to animal physiology, and give an example of the
following
- hyperosmotic regulator
- hyposmotic regulator
- Chloride cells
- Salt glands
- Rectal gland
- TMAO
- urea
- Anadromous
- Catadromous
- Stenohaline
- Euryhaline
Chapter 28 Excretion
REVIEW QUESTIONS
Chapter 29 Desert Mammals
REVIEW QUESTIONS